Virology

INTRODUCTION TO VIROLOGY

1. Introduction to virology

    • Discovery of viruses (Overview of Virology)
    • Nature and definition of viruses (Overview of Virology, why should we know about virology and its importance)
    • General properties of viruses (Viral structures, types of viral genomes, important definitions and composition of viral particles)
    • Concept of viroids, virusoids, satellite viruses and prions (overview of viral structure)
    • Introduction to virus structure (Structural components- a brief idea)

2. Isolation, purification and cultivation of viruses

  • Cultivation of viruses (Virus cultivation under laboratory conditions)
  • Isolation of viruses (Overview of methods of cultivation and isolation of viruses)
  • Structural investigations of cells and virions (various methods for investigating viral Structures, Structural changes in virus infected cells)
  • Centrifugation and electrophoretic techniques (Use of electrophoretic and centrifugation techniques for investigation of viruses)
  • Detection of viruses and virus components (Various methods of detection of viruses and viral components)
  • Infectivity assays  ( various methods of performing viral infectivity assays)

3. Viral Taxonomy, multiplication and replication

  • Baltimore’s Classification (ICTV nomenclature, classification, phylogenetic tree, classification based on viral genome and genome replication)
  • Modern virus classification and nomenclature
  • Replication strategies of viruses as per Baltimore classification
  • Assembly, maturation and release of virions (Assembly in icosahedral and helical viruses, budding through cell membranes, De novo synthesis of viral membranes, budding, lysis)
  • Interaction of viruses with cellular receptors and entry of viruses (Cellular receptors in interaction with viral particles)

4. Bacteriophages

5. Oncogenic viruses

  • Concepts of oncogenes (Overview of oncogenes)
  • Types of oncogenic DNA and RNA viruses (Features of oncogenic DNA and RNA viruses)
  • Proto-oncogenes (Basic idea of protooncogenes)
  • Tumor suppressor genes (Role of tumor suppressor genes)

6.Prevention and control of viral diseases

  • Antiviral compounds (Types and importance of antiviral agents)
  • Interferons (Features of interferons)
  • Viral vaccines (Features and types of viral vaccines)

7. Applications of Virology

 

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